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Rabbit polyclonal antibody to PFKFB2 (Y14)

Western blot (WB) analysis of PFKFB2 (Y14) pAb at 1:500 dilution Lane1:A549 whole cell lysate(40ug) Lane2:PC3 whole cell lysate(40ug) Lane3:MCF~7 whole cell lysate(40ug) Lane4:Hela whole cell lysate(40ug) Lane5:U~87MG whole cell lysate(40ug)

Rabbit polyclonal antibody to PFKFB2 (Y14)

货号：
53689
别名：
PFK~2 car; PFK~2 cardiac; 6~phosphofructo~2~kinase/fructose~2,6~bisphosphatase 2; 6PF~2~K/Fru~2,6~P2ase 2; PFK/FBPase 2; 6PF~2~K/Fru~2,6~P2ase heart~type isozyme; 6~phosphofructo~2~kinase; Fructose~2,6~bisphosphatase; PFKFB2
产品上架时间：
2024-01-01
应用：
WB IHC
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
O60825
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1180

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Rabbit polyclonal antibody to PFKFB2 (Y14)

Description
PFK~1 undergoes activation in the presence of elevated AMP. The most potent activator is fructose~2,6~bisphosphate, which is produced by PFK~2 from the same substrate, fructose 6~phosphate. PFK~2 is bifunctional and a key regulator for PFK~1. PFK~2 catalyzes the synthesis of fructose~2,6~bisphosphate, and contains fructose~2,6~biphosphatase activity that catalyzes the degradation of fructose~2,6~bisphosphate. PFK~2 is dimeric and isoenzymes include PFK~2 liver (PFKFB1, PFRX), PFK~2 cardiac (PFKFB2), PFK~2 placental (PFKFB3, inducible PFK~2) and PFK~2 testis (PFKFB4).

Description

PFK~1 undergoes activation in the presence of elevated AMP. The most potent activator is fructose~2,6~bisphosphate, which is produced by PFK~2 from the same substrate, fructose 6~phosphate. PFK~2 is bifunctional and a key regulator for PFK~1. PFK~2 catalyzes the synthesis of fructose~2,6~bisphosphate, and contains fructose~2,6~biphosphatase activity that catalyzes the degradation of fructose~2,6~bisphosphate. PFK~2 is dimeric and isoenzymes include PFK~2 liver (PFKFB1, PFRX), PFK~2 cardiac (PFKFB2), PFK~2 placental (PFKFB3, inducible PFK~2) and PFK~2 testis (PFKFB4).

Specification
Aliases	PFK~2 car; PFK~2 cardiac; 6~phosphofructo~2~kinase/fructose~2,6~bisphosphatase 2; 6PF~2~K/Fru~2,6~P2ase 2; PFK/FBPase 2; 6PF~2~K/Fru~2,6~P2ase heart~type isozyme; 6~phosphofructo~2~kinase; Fructose~2,6~bisphosphatase; PFKFB2
Swissprot	O60825
clone	2C10G5
WB Predicted band size	~58kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthetic peptide, corresponding to amino acids 1~50 of Human PFKFB2.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2