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Rabbit polyclonal antibody to TWEAK (P73)

Western blot (WB) analysis of TWEAK (P73) polyclonal antibody at 1:500 dilution Lane1:A549 whole cell lysate(40ug) Lane2:U~87MG whole cell lysate(40ug) Lane3:HEK293T whole cell lysate(40ug) Lane4:A2780 whole cell lysate(40ug) Lane5:SP2/0 whole cell lysate(40ug) Lane6:C6 whole cell lysate(40ug) Lane7:PC12 whole cell lysate(40ug)

Rabbit polyclonal antibody to TWEAK (P73)

货号：
53688
别名：
Tumor necrosis factor ligand superfamily member 12; APO3 ligand; TNF~related weak inducer of apoptosis; TWEAK; TNFSF12; APO3L; DR3LG; UNQ181/PRO207
产品上架时间：
2024-01-01
应用：
WB IHC IF
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
O43508
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1180

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Rabbit polyclonal antibody to TWEAK (P73)

Description
TWEAK is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. It is widely expressed, has high constitutive expression in heart placenta, lung, muscle, kidney, pancreas, and HUVEC. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. TWEAK can induce apoptosis via multiple pathways of cell death in a cell type specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis.

Description

TWEAK is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. It is widely expressed, has high constitutive expression in heart placenta, lung, muscle, kidney, pancreas, and HUVEC. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. TWEAK can induce apoptosis via multiple pathways of cell death in a cell type specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis.

Specification
Aliases	Tumor necrosis factor ligand superfamily member 12; APO3 ligand; TNF~related weak inducer of apoptosis; TWEAK; TNFSF12; APO3L; DR3LG; UNQ181/PRO207
Swissprot	O43508
clone	7D3F6
WB Predicted band size	~27kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human
Immunogen	Synthetic peptide, corresponding to amino acids 51~100 of Human TWEAK.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2