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Rabbit polyclonal antibody to TAF II p135/p105 (E977)
-
货号:
53607 -
别名:
Transcription initiation factor TFIID subunit 4; RNA polymerase II TBP~associated factor subunit C; TBP~associated factor 4; Transcription initiation factor TFIID 130 kDa subunit; TAF(II)130; TAFII~130; TAFII130; Transcription initiation factor TFIID 135 kDa subunit; TAF(II)135; TAFII~135; TAFII135; TAF4; TAF2C; TAF2C1; TAF4A; TAFII130; TAFII135; Transcription initiation factor TFIID subunit 4B; Transcription initiation factor TFIID 105 kDa subunit; TAF(II)105; TAFII~105; TAFII105; TAF4B; TAF2C2; TAFII105 -
应用:
WB IHC -
反应种属:
Human,Mouse,Rat -
抗体类型:
Primary antibody -
Swissprot:
O00268/Q92750 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180
Rabbit polyclonal antibody to TAF II p135/p105 (E977)
Description |
|---|
TAF II p105, also called TAF4B, is a celltype specific transcriptional co~activator that is a component of the TFIID complex. Expressed primarily in B cells and ovarian granulosa cells, TAF II p105 can interact with OCBA/POU2AF1 to activate B cell~specific octamerdependent transcription. Additionally, TAF II p105 plays an important role in co~activating the transcription factor NFκB and is essential for activation of anti~apoptotic genes such as TNFAIP3. TAF II p135, also known as TAF4, TAF2C, TAF2C1, TAF4A or TAFII130, is a 1,085 amino acid subunit of TFIID that accelerates transcriptional activation triggered by thyroid hormone (TR) or retinoic acid (RA). Localized to the nucleus, TAF II p135 contains one TAFH domain and is thought to bind to proteins that contain glutamine~rich domains, such as the transcription factor CREB. |
Specification |
|
|---|---|
| Aliases | Transcription initiation factor TFIID subunit 4; RNA polymerase II TBP~associated factor subunit C; TBP~associated factor 4; Transcription initiation factor TFIID 130 kDa subunit; TAF(II)130; TAFII~130; TAFII130; Transcription initiation factor TFIID 135 kDa subunit; TAF(II)135; TAFII~135; TAFII135; TAF4; TAF2C; TAF2C1; TAF4A; TAFII130; TAFII135; Transcription initiation factor TFIID subunit 4B; Transcription initiation factor TFIID 105 kDa subunit; TAF(II)105; TAFII~105; TAFII105; TAF4B; TAF2C2; TAFII105 |
| Swissprot | O00268/Q92750 |
| clone | 1H8F10 |
| WB Predicted band size | ~135kDa,~105kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide, corresponding to amino acids 951~1000 of Human TAF II p135. |
| Formulation | 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 |
Application |
|
|---|---|
| WB | 1/500~1/1000 |
| IHC | 1/50~1/200 |
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#53607
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