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Rabbit polyclonal antibody to AR~α1A (Q365)

Western blot (WB) analysis of AR~α1A (Q365) pAb at 1:500 dilution Lane1:HepG2 whole cell lysate(40ug) Lane2:PC3 whole cell lysate(40ug) Lane3:LO2 whole cell lysate(40ug) Lane4:HEK293T whole cell lysate(40ug)

Rabbit polyclonal antibody to AR~α1A (Q365)

货号：
53597
别名：
Alpha~1A adrenergic receptor; Alpha~1A adrenoreceptor; Alpha~1A adrenoceptor; Alpha~1C adrenergic receptor; Alpha~adrenergic receptor 1c; ADRA1A; ADRA1C; α1A~AR; α~1A AR
产品上架时间：
2024-01-01
应用：
WB IHC IF
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P35348
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1280

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Rabbit polyclonal antibody to AR~α1A (Q365)

Description
α1A~adrenergic receptors (α1A~ARs) mediate actions in the sympathetic nervous system through the binding of the catecholamines, epinephrine and norepinephrine. α1A~AR couples to Gq/11 and regulates blood pressure due to changes in vascular tone and cardiac output. Alternative splicing of the ADRA1A gene generates four isoforms with distinct C~termini, and the different expression profile of these subtypes produces distinct patterns of activation. α1A~AR transcripts are abundant in heart, brain, liver and prostate. α1A~AR transcript sizes of 6.0, 4.0, 3.0, and 2.0 kb have been detected in liver. Transcripts of 6.0, 4.0 and 3.0 kb have been detected in heart, and transcripts of 6.0 and 4.0 kb have been detected in prostate

Description

α1A~adrenergic receptors (α1A~ARs) mediate actions in the sympathetic nervous system through the binding of the catecholamines, epinephrine and norepinephrine. α1A~AR couples to Gq/11 and regulates blood pressure due to changes in vascular tone and cardiac output. Alternative splicing of the ADRA1A gene generates four isoforms with distinct C~termini, and the different expression profile of these subtypes produces distinct patterns of activation. α1A~AR transcripts are abundant in heart, brain, liver and prostate. α1A~AR transcript sizes of 6.0, 4.0, 3.0, and 2.0 kb have been detected in liver. Transcripts of 6.0, 4.0 and 3.0 kb have been detected in heart, and transcripts of 6.0 and 4.0 kb have been detected in prostate

Specification
Aliases	Alpha~1A adrenergic receptor; Alpha~1A adrenoreceptor; Alpha~1A adrenoceptor; Alpha~1C adrenergic receptor; Alpha~adrenergic receptor 1c; ADRA1A; ADRA1C; α1A~AR; α~1A AR
Swissprot	P35348
clone	1C9G10
WB Predicted band size	~51kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human
Immunogen	Synthetic peptide, corresponding to amino acids 350~400 of Human AR~α1A.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2