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Rabbit polyclonal antibody to Cdc27 (K390)

Western blot (WB) analysis of Cdc27 (K390) pAb at 1:500 dilution Lane1:MCF~7 whole cell lysate(40ug) Lane2:HEK293T whole cell lysate(40ug) Lane3:K562 whole cell lysate(40ug)

Rabbit polyclonal antibody to Cdc27 (K390)

货号：
53592
别名：
Cell division cycle protein 27 homolog; Anaphase~promoting complex subunit 3; APC3; CDC27 homolog; CDC27Hs; H~NUC; CDC27; ANAPC3; D0S1430E; D17S978E
产品上架时间：
2024-01-01
应用：
WB IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P30260
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1280

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Rabbit polyclonal antibody to Cdc27 (K390)

Description
Cell cycle events are regulated by the sequential activation and deactivation of cyclin dependent kinases (Cdks) and by the proteolysis of cyclins. The cell division cycle (Cdc) genes are required at various points in the cell cycle. Cdc37 appears to facilitate Cdk4/cyclin D1 complex formation and has been shown to form a stable complex with HSP 90. Cdc34, Cdc27 and Cdc16 function as ubiquitinconjugating enzymes. Cdc34 is thought to be the structural and functional homolog of Saccharomyces cerevisiae Cdc34, which is essential for the G1 to S phase transition. Cdc16 and Cdc27 are components of the APC (anaphasepromoting complex) which ubiquitinates cyclin B, resulting in cyclin B/Cdk complex degradation.

Description

Cell cycle events are regulated by the sequential activation and deactivation of cyclin dependent kinases (Cdks) and by the proteolysis of cyclins. The cell division cycle (Cdc) genes are required at various points in the cell cycle. Cdc37 appears to facilitate Cdk4/cyclin D1 complex formation and has been shown to form a stable complex with HSP 90. Cdc34, Cdc27 and Cdc16 function as ubiquitinconjugating enzymes. Cdc34 is thought to be the structural and functional homolog of Saccharomyces cerevisiae Cdc34, which is essential for the G1 to S phase transition. Cdc16 and Cdc27 are components of the APC (anaphasepromoting complex) which ubiquitinates cyclin B, resulting in cyclin B/Cdk complex degradation.

Specification
Aliases	Cell division cycle protein 27 homolog; Anaphase~promoting complex subunit 3; APC3; CDC27 homolog; CDC27Hs; H~NUC; CDC27; ANAPC3; D0S1430E; D17S978E
Swissprot	P30260
clone	8G7D7
WB Predicted band size	~80,92kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human
Immunogen	Synthetic peptide, corresponding to amino acids 360~410 of Human Cdc27.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2