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Rabbit polyclonal antibody to PFKFB1/4 (E349)

Western blot (WB) analysis of PFKFB1/4 (E349) pAb at 1:1000 dilution Lane1:K562 whole cell lysate(40ug) Lane2:A549 whole cell lysate(40ug) Lane3:PC12 whole cell lysate(40ug) Lane4:AML~12 whole cell lysate(40ug)

Rabbit polyclonal antibody to PFKFB1/4 (E349)

货号：
53555
别名：
PFK~2 liver; PFKFB1; PFRX; F6PK; 6PF~2~K/Fru~2; 6~P2ASE liver isozyme; 6~phosphofructo~2~kinase/fructose~2; 6~biphosphatase 1; PFK~2 testis; 6~phosphofructo~2~kinase/fructose~2,6~bisphosphatase 4; 6PF~2~K/Fru~2,6~P2ase 4; PFK/FBPase 4; 6PF~2~K/Fru~2,6~P2ase testis~type isozyme; 6~phosphofructo~2~kinase; Fructose~2,6~bisphosphatase; PFKFB4
产品上架时间：
2024-01-01
应用：
WB
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P16118/Q16877
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1180

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Rabbit polyclonal antibody to PFKFB1/4 (E349)

Description
PFK~1 undergoes activation in the presence of elevated AMP. The most potent activator is fructose~2,6~bisphosphate, which is produced by PFK~2 from the same substrate, fructose 6~phosphate. PFK~2 is bifunctional and a key regulator for PFK~1. PFK~2 catalyzes the synthesis of fructose~2,6~bisphosphate, and contains fructose~2,6~biphosphatase activity that catalyzes the degradation of fructose~2,6~bisphosphate. PFK~2 is dimeric and isoenzymes include PFK~2 liver (PFKFB1, PFRX), PFK~2 cardiac (PFKFB2), PFK~2 placental (PFKFB3, inducible PFK~2) and PFK~2 testis (PFKFB4).

Description

PFK~1 undergoes activation in the presence of elevated AMP. The most potent activator is fructose~2,6~bisphosphate, which is produced by PFK~2 from the same substrate, fructose 6~phosphate. PFK~2 is bifunctional and a key regulator for PFK~1. PFK~2 catalyzes the synthesis of fructose~2,6~bisphosphate, and contains fructose~2,6~biphosphatase activity that catalyzes the degradation of fructose~2,6~bisphosphate. PFK~2 is dimeric and isoenzymes include PFK~2 liver (PFKFB1, PFRX), PFK~2 cardiac (PFKFB2), PFK~2 placental (PFKFB3, inducible PFK~2) and PFK~2 testis (PFKFB4).

Specification
Aliases	PFK~2 liver; PFKFB1; PFRX; F6PK; 6PF~2~K/Fru~2; 6~P2ASE liver isozyme; 6~phosphofructo~2~kinase/fructose~2; 6~biphosphatase 1; PFK~2 testis; 6~phosphofructo~2~kinase/fructose~2,6~bisphosphatase 4; 6PF~2~K/Fru~2,6~P2ase 4; PFK/FBPase 4; 6PF~2~K/Fru~2,6~P2ase testis~type isozyme; 6~phosphofructo~2~kinase; Fructose~2,6~bisphosphatase; PFKFB4
Swissprot	P16118/Q16877
clone	4F6D5
WB Predicted band size	~54kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthetic peptide, corresponding to amino acids 320~370 of Human PFKFB1.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2