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Rabbit polyclonal antibody to CBP20 (R21)

Western blot (WB) analysis of CBP20 (R21) pAb at 1:1000 dilution Lane1:MCF~7 whole cell lysate(40ug) Lane2:L02 whole cell lysate(40ug) Lane3:CT26 whole cell lysate(40ug) Lane4:H9C2 whole cell lysate(40ug)

Rabbit polyclonal antibody to CBP20 (R21)

货号：
53531
别名：
Nuclear cap~binding protein subunit 2; 20 kDa nuclear cap~binding protein; Cell proliferation~inducing gene 55 protein; NCBP 20 kDa subunit; CBP20; NCBP~interacting protein 1; NIP1; NCBP2; CBP20; ORF Names: PIG55
产品上架时间：
2024-01-01
应用：
WB IHC IF IP
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P52298
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1280

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Rabbit polyclonal antibody to CBP20 (R21)

Description
In eukaryotes, the majority of mRNAs have an m(7)G cap, which is added cotranscriptionally and plays a critical role in many aspects of mRNA metabolism. The effect of the cap on translation is mediated by the initiation factor eIF~4F, whereas the effect on pre~mRNA splicing involves a nuclear complex (CBC). CBC consists of two cap binding proteins, CBP20 and CBP80, which mediate the stimulatory functions of the cap in pre~mRNA splicing, 3' end formation and U snRNA export. The genes CBC1 and CBC2 encode CBP80 and CBP20, respectively. CBP80 comprises three domains, each containing a MIF4G domain. CBP20 has an RNAP fold and associates with the second and third domains of CBP80.

Description

In eukaryotes, the majority of mRNAs have an m(7)G cap, which is added cotranscriptionally and plays a critical role in many aspects of mRNA metabolism. The effect of the cap on translation is mediated by the initiation factor eIF~4F, whereas the effect on pre~mRNA splicing involves a nuclear complex (CBC). CBC consists of two cap binding proteins, CBP20 and CBP80, which mediate the stimulatory functions of the cap in pre~mRNA splicing, 3' end formation and U snRNA export. The genes CBC1 and CBC2 encode CBP80 and CBP20, respectively. CBP80 comprises three domains, each containing a MIF4G domain. CBP20 has an RNAP fold and associates with the second and third domains of CBP80.

Specification
Aliases	Nuclear cap~binding protein subunit 2; 20 kDa nuclear cap~binding protein; Cell proliferation~inducing gene 55 protein; NCBP 20 kDa subunit; CBP20; NCBP~interacting protein 1; NIP1; NCBP2; CBP20; ORF Names: PIG55
Swissprot	P52298
clone	6G5G7
WB Predicted band size	~18kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthetic peptide, corresponding to amino acids N~terminus of Human CBP20.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2