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Rabbit polyclonal antibody to BAF53 (W237)

Western blot (WB) analysis of BAF53 (W237) pAb at 1:500 dilution Lane1:PC3 whole cell lysate(40ug) Lane2:MCF~7 whole cell lysate(40ug) Lane3:The Uterus tissue lysate of Rat(40ug) Lane4:The Uterus tissue lysate of Mouse(40ug)

Rabbit polyclonal antibody to BAF53 (W237)

货号：
53477
别名：
Actin~like protein 6A; 53 kDa BRG1~associated factor A; Actin~related protein Baf53a; ArpNbeta; BRG1~associated factor 53A; BAF53A; INO80 complex subunit K; ACTL6A; BAF53; BAF53A; INO80K
产品上架时间：
2024-01-01
应用：
WB IHC
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
O96019
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1280

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Rabbit polyclonal antibody to BAF53 (W237)

Description
The SWI/SNF complex regulates gene expression via ATP~dependent chromatin remodeling. Brm (SNF2~a), Brg~1 (SNF2~b), Ini1 (integrase interactor 1, SNF5), BAF53 (ARPnβ), BAF57, BAF155 (SRG3), and BAF170 make up the functional core. BAF53 homologues from yeast to humans contain a conserved N~terminal motif, which contains residues at serine 2 and tyrosine 6, which play important roles in BAF53 activity. The BAF53 protein shuttles between the nucleus and cytoplasm. BAF53 also forms a complex with TIP49 and TIP48, which mediates c~Myc oncogenic activity.

Description

The SWI/SNF complex regulates gene expression via ATP~dependent chromatin remodeling. Brm (SNF2~a), Brg~1 (SNF2~b), Ini1 (integrase interactor 1, SNF5), BAF53 (ARPnβ), BAF57, BAF155 (SRG3), and BAF170 make up the functional core. BAF53 homologues from yeast to humans contain a conserved N~terminal motif, which contains residues at serine 2 and tyrosine 6, which play important roles in BAF53 activity. The BAF53 protein shuttles between the nucleus and cytoplasm. BAF53 also forms a complex with TIP49 and TIP48, which mediates c~Myc oncogenic activity.

Specification
Aliases	Actin~like protein 6A; 53 kDa BRG1~associated factor A; Actin~related protein Baf53a; ArpNbeta; BRG1~associated factor 53A; BAF53A; INO80 complex subunit K; ACTL6A; BAF53; BAF53A; INO80K
Swissprot	O96019
clone	1D6C10
WB Predicted band size	~47kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthetic peptide, corresponding to amino acids 211~260 of Human BAF53.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2