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Rabbit polyclonal antibody to NOS1 (Y846)

Western blot (WB) analysis of NOS1 (Y846) pAb at 1:500 dilution Lane1:PC3 whole cell lysate(40ug) Lane2:A549 whole cell lysate(40ug) Lane3:U~87MG whole cell lysate(20ug) Lane4:C6 whole cell lysate(40ug) Lane5:BV2 whole cell lysate(40ug)

Rabbit polyclonal antibody to NOS1 (Y846)

货号：
53444
别名：
Nitric oxide synthase, brain; Constitutive NOS; NC~NOS; NOS type I; Neuronal NOS; N~NOS; nNOS; Peptidyl~cysteine S~nitrosylase NOS1; bNOS; NOS1
产品上架时间：
2024-01-01
应用：
WB IHC IF
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P29475
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1280

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Rabbit polyclonal antibody to NOS1 (Y846)

Description
NOS activity requires homodimerization as well as three cosubstrates (L~arginine, NADPH and O2) and five cofactors or prosthetic groups (FAD, FMN, calmodulin, tetrahydrobiopterin and heme). Several distinct NOS isoforms have been described and been shown to represent the products of three distinct genes. These include two constitutive Ca2+/CaM~dependent forms of NOS, including NOS1 (also designated ncNOS) whose activity was first identified in neurons, and NOS3 (also designated ecNOS), first identified in endothelial cells.

Description

NOS activity requires homodimerization as well as three cosubstrates (L~arginine, NADPH and O2) and five cofactors or prosthetic groups (FAD, FMN, calmodulin, tetrahydrobiopterin and heme). Several distinct NOS isoforms have been described and been shown to represent the products of three distinct genes. These include two constitutive Ca2+/CaM~dependent forms of NOS, including NOS1 (also designated ncNOS) whose activity was first identified in neurons, and NOS3 (also designated ecNOS), first identified in endothelial cells.

Specification
Aliases	Nitric oxide synthase, brain; Constitutive NOS; NC~NOS; NOS type I; Neuronal NOS; N~NOS; nNOS; Peptidyl~cysteine S~nitrosylase NOS1; bNOS; NOS1
Swissprot	P29475
clone	9H3B6
WB Predicted band size	~160kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthetic peptide, corresponding to amino acids 815~862 of Human NOS1.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2