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Rabbit polyclonal antibody to Ku~70 (S1)

Western blot (WB) analysis of Ku~70 (S1) pAb at 1:500 dilution Lane1:MCF~7 whole cell lysate(2.5ug) Lane2:HEK293T whole cell lysate(2.5ug) Lane3:PC12 whole cell lysate(20ug) Lane4:The Kidney tissue lysate of Mouse(40ug) Lane5:AML~12 whole cell lysate(40ug) Lane6:3T3~L1 whole cell lysate(40ug)

Rabbit polyclonal antibody to Ku~70 (S1)

货号：
53441
别名：
X~ray repair cross~complementing protein 6; 5'~deoxyribose~5~phosphate lyase Ku70; 5'~dRP lyase Ku70; 70 kDa subunit of Ku antigen; ATP~dependent DNA helicase 2 subunit 1; ATP~dependent DNA helicase II 70 kDa subunit; CTC box~binding factor 75 kDa subunit; CTC75; CTCBF; DNA repair protein XRCC6; Lupus Ku autoantigen protein p70; Ku70; Thyroid~lupus autoantigen; TLAA; X~ray repair complementing defective repair in; Chinese hamster cells 6; XRCC6; G22P1
产品上架时间：
2024-01-01
应用：
WB IHC
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P12956
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1280

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Rabbit polyclonal antibody to Ku~70 (S1)

Description
The Ku protein is localized in the nucleus and is composed of subunits referred to as Ku~70 (or p70) and Ku~86 (or p86), which is also known by the synonym Ku~80 (or p80). Ku was first described as an autoantigen to which antibodies were produced in a patient with scleroderma~polymyositis overlap syndrome, and was later found in the sera of patients with other rheumatic diseases. Both subunits of the Ku protein have been cloned, and a number of functions have been proposed for Ku, including cell signaling, DNA replication and transcriptional activation.

Description

The Ku protein is localized in the nucleus and is composed of subunits referred to as Ku~70 (or p70) and Ku~86 (or p86), which is also known by the synonym Ku~80 (or p80). Ku was first described as an autoantigen to which antibodies were produced in a patient with scleroderma~polymyositis overlap syndrome, and was later found in the sera of patients with other rheumatic diseases. Both subunits of the Ku protein have been cloned, and a number of functions have been proposed for Ku, including cell signaling, DNA replication and transcriptional activation.

Specification
Aliases	X~ray repair cross~complementing protein 6; 5'~deoxyribose~5~phosphate lyase Ku70; 5'~dRP lyase Ku70; 70 kDa subunit of Ku antigen; ATP~dependent DNA helicase 2 subunit 1; ATP~dependent DNA helicase II 70 kDa subunit; CTC box~binding factor 75 kDa subunit; CTC75; CTCBF; DNA repair protein XRCC6; Lupus Ku autoantigen protein p70; Ku70; Thyroid~lupus autoantigen; TLAA; X~ray repair complementing defective repair in; Chinese hamster cells 6; XRCC6; G22P1
Swissprot	P12956
clone	6E1E7
WB Predicted band size	~70kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthetic peptide, corresponding to the N~terminus of Human Ku~70.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2