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Western blot (WB) analysis of Eg5 (P923) polyclonal antibody at 1:500 dilution
Lane1:Hela cell lysate
Lane2:sp2/0 cell lysate
Lane3:PC12 cell lysate
Rabbit polyclonal antibody to Eg5 (P923)
-
货号：
53407 -
别名：
Kinesin~like protein KIF11; Kinesin~like protein 1; Kinesin~like spindle protein HKSP; Kinesin~related motor protein Eg5; Thyroid receptor~interacting protein 5; TR~interacting protein 5; TRIP~5; KIF11; EG5; KNSL1; TRIP5 -
应用：
WB IHC IF -
反应种属：
Human,Mouse,Rat -
抗体类型：
Primary antibody -
Swissprot：
P52732 -
规格：
-
数量：
-+ -
说明书：
目录价¥1280
Rabbit polyclonal antibody to Eg5 (P923)
Description |
|---|
Eg5 (also known as Kinesin~like protein KIF11 or TRIP5) is a slow, plus~end~directed microtubule~based motor of the BimC kinesin family that is essential for bipolar spindle formation during eukaryotic cell division. When the expression of Eg5 is blocked, centrosome migration halts and cells are arrested in mitosis with monoastral microtubule arrays. Eg5 is phosphorylated on serine during S phase and on both serine and Thr 927 during mitosis, which regulates the association of Eg5 with the spindle apparatus (probably during early prophase). Eg5 is also known to be a member of the thyroid receptor interacting protein (TRIP) family, and interacts with the thyroid hormone receptor only in the presence of thyroid hormone. |
Specification |
|
|---|---|
| Aliases | Kinesin~like protein KIF11; Kinesin~like protein 1; Kinesin~like spindle protein HKSP; Kinesin~related motor protein Eg5; Thyroid receptor~interacting protein 5; TR~interacting protein 5; TRIP~5; KIF11; EG5; KNSL1; TRIP5 |
| Swissprot | P52732 |
| clone | 1G3A7 |
| WB Predicted band size | ~119kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide, corresponding to amino acids 900~950 of Human Eg5. |
| Formulation | 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 |
Application |
|
|---|---|
| WB | 1/500~1/1000 |
| IHC | 1/50~1/200 |
| IF/ICC | 1/50~1/200 |
For Reseach Only
Application Key：WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#53407
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