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Rabbit polyclonal antibody to hnRPD (H79)

Western blot (WB) analysis of hnRPD (H79) polyclonal antibody at 1:500 dilution Lane1:Hela whole cell lysate(40ug) Lane2:HEK293T whole cell lysate(40ug) Lane3:PC12 whole cell lysate(40ug) Lane4:BV2 whole cell lysate(40ug)

Rabbit polyclonal antibody to hnRPD (H79)

货号：
53406
别名：
Heterogeneous nuclear ribonucleoprotein D0; hnRNP D0; AU~rich element RNA~binding protein 1; AUF1; HNRPD; HNRNPD
产品上架时间：
2024-01-01
应用：
WB IHC IF
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
Q14103
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1280

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Rabbit polyclonal antibody to hnRPD (H79)

Description
hnRNP D/AUF1 binds with high affinity to RNA molecules that contain AU~rich elements (AREs) found within the 3' untranslated regions of many protooncogenes and cytokine mRNAs. It also binds to double and single stranded DNA sequences in a specific manner and functions a transcription factor. Each of the RNA~binding domains specifically can bind solely to a single stranded nonmonotonous 5'~UUAG~3' sequence and also weaker to the single~stranded 5'~TTAGGG~3' telomeric DNA repeat. It may be involved in translationally coupled mRNA turnover (referenced from swissprot).

Description

hnRNP D/AUF1 binds with high affinity to RNA molecules that contain AU~rich elements (AREs) found within the 3' untranslated regions of many protooncogenes and cytokine mRNAs. It also binds to double and single stranded DNA sequences in a specific manner and functions a transcription factor. Each of the RNA~binding domains specifically can bind solely to a single stranded nonmonotonous 5'~UUAG~3' sequence and also weaker to the single~stranded 5'~TTAGGG~3' telomeric DNA repeat. It may be involved in translationally coupled mRNA turnover (referenced from swissprot).

Specification
Aliases	Heterogeneous nuclear ribonucleoprotein D0; hnRNP D0; AU~rich element RNA~binding protein 1; AUF1; HNRPD; HNRNPD
Swissprot	Q14103
clone	3F6B2
WB Predicted band size	~38kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthetic peptide, corresponding to amino acids 46~98 of Human hnRPD.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2