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Rabbit polyclonal antibody to MITF (G174)

Western blot (WB) analysis of MITF polyclonal antibody at 1:1000 dilution Lane1:The heart tissue lysate of Rat(30ug) Lane2:The kidney tissue lysate of Mouse(30ug) Lane3:CT~26 whole cell lysate(30ug) Lane4:PC12 whole cell lysate(30ug) Lane5:A2780 whole cell lysate(30ug)

Rabbit polyclonal antibody to MITF (G174)

货号：
53370
别名：
Microphthalmia~associated transcription factor; Class E basic helix~loop~helix protein 32; bHLHe32
产品上架时间：
2024-01-01
应用：
WB
反应种属：
Human,Rat,Mouse
抗体类型：
Primary antibody
Swissprot：
O75030
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1280

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Rabbit polyclonal antibody to MITF (G174)

Description
Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to M~boxes (5'~TCATGTG~3') and symmetrical DNA sequences (E~boxes) (5'~CACGTG~3') found in the promoters of target genes, such as BCL2 and tyrosinase (TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase (TYR) and tyrosinase~related protein 1 (TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest~derived melanocytes, mast cells, osteoclasts and optic cup~derived retinal pigment epithelium.

Description

Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to M~boxes (5'~TCATGTG~3') and symmetrical DNA sequences (E~boxes) (5'~CACGTG~3') found in the promoters of target genes, such as BCL2 and tyrosinase (TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase (TYR) and tyrosinase~related protein 1 (TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest~derived melanocytes, mast cells, osteoclasts and optic cup~derived retinal pigment epithelium.

Specification
Aliases	Microphthalmia~associated transcription factor; Class E basic helix~loop~helix protein 32; bHLHe32
Swissprot	O75030
clone	10C7H10
WB Predicted band size	~60~75kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human,Rat,Mouse
Immunogen	Synthetic peptide, corresponding to Human MITF.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.