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Rabbit polyclonal antibody to SAE2 (S621)

Western blot (WB) analysis of SAE2 (S621) polyclonal antibody at 1:500 dilution Lane1:A549 whole cell lysate(40ug) Lane2:HEK293T whole cell lysate(40ug) Lane3:H1792 whole cell lysate(40ug) Lane4:PC12 whole cell lysate(40ug) Lane5:BV2 whole cell lysate(40ug)

Rabbit polyclonal antibody to SAE2 (S621)

货号：
53355
别名：
SUMO~activating enzyme subunit 2; Anthracycline~associated resistance ARX; Ubiquitin~like 1~activating enzyme E1B; Ubiquitin~like modifier~activating enzyme 2; UBA2; SAE2; UBLE1B; HRIHFB2115
产品上架时间：
2024-01-01
应用：
WB IHC IF
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
Q9UBT2
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1180

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Rabbit polyclonal antibody to SAE2 (S621)

Description
The human UBiquitin Activating domain 2 (UBA2) gene is located on chromosome 19q12. Human UBA2 could form a beta mercaptoethanol~sensitive conjugate with members of the sentrin family, but not with ubiquitin of NEDD8 in the presence of AOS1. The recombinant proteins, Sua1p and hUba2, form a complex. In this complex, hUba2 binds SUMO~1, which gives the complex the activity of the SUMO~1 activating enzyme. Therefore, UBA2 has been found to be a component of the sentrin~activating enzyme complex.

Description

The human UBiquitin Activating domain 2 (UBA2) gene is located on chromosome 19q12. Human UBA2 could form a beta mercaptoethanol~sensitive conjugate with members of the sentrin family, but not with ubiquitin of NEDD8 in the presence of AOS1. The recombinant proteins, Sua1p and hUba2, form a complex. In this complex, hUba2 binds SUMO~1, which gives the complex the activity of the SUMO~1 activating enzyme. Therefore, UBA2 has been found to be a component of the sentrin~activating enzyme complex.

Specification
Aliases	SUMO~activating enzyme subunit 2; Anthracycline~associated resistance ARX; Ubiquitin~like 1~activating enzyme E1B; Ubiquitin~like modifier~activating enzyme 2; UBA2; SAE2; UBLE1B; HRIHFB2115
Swissprot	Q9UBT2
clone	4A6H1
WB Predicted band size	~90kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthetic peptide, corresponding to amino acids 598~640 of Human SAE2.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2