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Rabbit polyclonal antibody to NUB1 (Y601)

Western blot (WB) analysis of NUB1 (Y601) pAb at 1:500 dilution Lane1:HEK293T whole cell lysate(10ug) Lane2:A549 whole cell lysate(10ug) Lane3:U~87MG whole cell lysate(10ug) Lane4:MCF~7 whole cell lysate(10ug) Lane5:PC3 whole cell lysate(10ug) Lane6:PC12 whole cell lysate(40ug) Lane7:AML~12 whole cell lysate(40ug)

Rabbit polyclonal antibody to NUB1 (Y601)

货号：
53344
别名：
NEDD8 ultimate buster 1; Negative regulator of ubiquitin~like proteins 1; Renal carcinoma antigen NY~REN~18; NUB1; NYREN18
产品上架时间：
2024-01-01
应用：
WB IHC IP
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
Q9Y5A7
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1280

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Rabbit polyclonal antibody to NUB1 (Y601)

Description
NEDD8 is a ubiquitin~like protein that controls vital biological events through its conjugation to cullin proteins. NEDD8 ultimate buster~1 (NUB1), is a negative regulator of the NEDD8 system that recruits NEDD8 and its conjugates to the proteasome for degradation. It is, therefore a cell growth regulator. The UBA domain of NUB1 is the specific acceptor for the linear ubiquitin precursor. NUB1 is composed of 601 amino acids. It is an interferon~inducible protein and predominantly localizes in the nucleus. NUB1 is specifically expressed in adult human testis, ovary, heart, and skeletal muscle tissues.

Description

NEDD8 is a ubiquitin~like protein that controls vital biological events through its conjugation to cullin proteins. NEDD8 ultimate buster~1 (NUB1), is a negative regulator of the NEDD8 system that recruits NEDD8 and its conjugates to the proteasome for degradation. It is, therefore a cell growth regulator. The UBA domain of NUB1 is the specific acceptor for the linear ubiquitin precursor. NUB1 is composed of 601 amino acids. It is an interferon~inducible protein and predominantly localizes in the nucleus. NUB1 is specifically expressed in adult human testis, ovary, heart, and skeletal muscle tissues.

Specification
Aliases	NEDD8 ultimate buster 1; Negative regulator of ubiquitin~like proteins 1; Renal carcinoma antigen NY~REN~18; NUB1; NYREN18
Swissprot	Q9Y5A7
clone	9D10H3
WB Predicted band size	~70kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthetic peptide, corresponding to amino acids 570~621 of Human NUB1.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2