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Western blot (WB) analysis of HYD (T14) polyclonal antibody at 1:500 dilution Lane1:CT26 whole cell lysate(40ug) Lane2:PC12 whole cell lysate(40ug) Lane3:HEK293T whole cell lysate(40ug) Lane4:HK~2 whole cell lysate(40ug)

Rabbit polyclonal antibody to HYD (T14)

货号：
53341
别名：
E3 ubiquitin~protein ligase UBR5; E3 ubiquitin~protein ligase, HECT domain~containing 1; Hyperplastic discs protein homolog; hHYD; Progestin~induced protein; UBR5; EDD; EDD1; HYD; KIAA0896
产品上架时间：
2024-01-01
应用：
WB IHC
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
O95071
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1280

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Rabbit polyclonal antibody to HYD (T14)

Description
EDD (for E3 identified by Differential Display) is a progestin~regulated gene that was isolated from T~47D human breast cancer cells. Based on sequence homology, EDD appears to be a human homolog of the Drosophila hyperplastic discs (hyd) gene, a tumor suppressor gene that is required for control of imaginal disc growth. EDD contains a HECT domain in the carboxy terminus. HECT domain~containing proteins function as ubiquitin~protein ligases, or E3 enzymes. EDD has been shown to bind to ubiquitin, and like other HECT family proteins, may function as an E3 ubiquitin~protein ligase.

Description

EDD (for E3 identified by Differential Display) is a progestin~regulated gene that was isolated from T~47D human breast cancer cells. Based on sequence homology, EDD appears to be a human homolog of the Drosophila hyperplastic discs (hyd) gene, a tumor suppressor gene that is required for control of imaginal disc growth. EDD contains a HECT domain in the carboxy terminus. HECT domain~containing proteins function as ubiquitin~protein ligases, or E3 enzymes. EDD has been shown to bind to ubiquitin, and like other HECT family proteins, may function as an E3 ubiquitin~protein ligase.

Specification
Aliases	E3 ubiquitin~protein ligase UBR5; E3 ubiquitin~protein ligase, HECT domain~containing 1; Hyperplastic discs protein homolog; hHYD; Progestin~induced protein; UBR5; EDD; EDD1; HYD; KIAA0896
Swissprot	O95071
clone	6F7A7
WB Predicted band size	~309kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthetic peptide, corresponding to amino acids 1~50 of Human HYD.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2