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Rabbit polyclonal antibody to FGFR1 (I648)

Western blot (WB) analysis of FGFR1/Flg (I648) pAb at 1:500 dilution Lane1:HEK293T whole cell lysate(40ug) Lane2:786~0 whole cell lysate(40ug) Lane3:U~251MG whole cell lysate(40ug) Lane4:PC12 whole cell lysate(40ug) Lane5:MEF whole cell lysate(40ug)

Rabbit polyclonal antibody to FGFR1 (I648)

货号：
53335
别名：
Fibroblast growth factor receptor 1; FGFR~1; 2.7.10.1; Basic fibroblast growth factor receptor 1; BFGFR; bFGF~R~1; Fms~like tyrosine kinase 2; FLT~2; N~sam; Proto~oncogene c~Fgr; CD331; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR; FGFR1
产品上架时间：
2024-01-01
应用：
WB IF
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P11362
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1180

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Rabbit polyclonal antibody to FGFR1 (I648)

Description
FGFR1 (fibroblast growth factor receptor 1) is a member of the fibroblast growth factor receptor family containing an Ig~like domain and a tyrosine kinase domain. This receptor has multiple isoforms and is a Type I membrane protein. FGFR1 is a widely expressed membrane receptor, with distinct isoforms expressed in specific tissues. FGFR1 binds fibroblast growth factor and induces mitogenesis and cellular differentiation. Defects in FGFR1 result in Pfeiffer syndrome associated with craniosynostosis. FGFR1 can be modified by phosphorylation and can bind basic/acidic fibroblast factor depending on the receptor isoform. FGFR1 has been shown to interact with N~cadherin and NCAM.

Description

FGFR1 (fibroblast growth factor receptor 1) is a member of the fibroblast growth factor receptor family containing an Ig~like domain and a tyrosine kinase domain. This receptor has multiple isoforms and is a Type I membrane protein. FGFR1 is a widely expressed membrane receptor, with distinct isoforms expressed in specific tissues. FGFR1 binds fibroblast growth factor and induces mitogenesis and cellular differentiation. Defects in FGFR1 result in Pfeiffer syndrome associated with craniosynostosis. FGFR1 can be modified by phosphorylation and can bind basic/acidic fibroblast factor depending on the receptor isoform. FGFR1 has been shown to interact with N~cadherin and NCAM.

Specification
Aliases	Fibroblast growth factor receptor 1; FGFR~1; 2.7.10.1; Basic fibroblast growth factor receptor 1; BFGFR; bFGF~R~1; Fms~like tyrosine kinase 2; FLT~2; N~sam; Proto~oncogene c~Fgr; CD331; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR; FGFR1
Swissprot	P11362
clone	4E10D5
WB Predicted band size	~92,120,145kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthetic peptide, corresponding to amino acids 621~670 of Human FGFR1.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2