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Rabbit polyclonal antibody to PLC γ2 (R747)

Western blot (WB) analysis of PLC γ2 (R747) pAb at 1:500 dilution Lane1:PC3 whole cell lysate(40ug) Lane2:BV2 whole cell lysate(40ug) Lane3:Hela whole cell lysate(40ug)

Rabbit polyclonal antibody to PLC γ2 (R747)

货号：
53324
别名：
1~phosphatidylinositol 4,5~bisphosphate phosphodiesterase gamma~2; Phosphoinositide phospholipase C~gamma~2; Phospholipase C~IV; PLC~IV; Phospholipase C~gamma~2; PLC~gamma~2; PLCG2; PLCγ2; PLC~γ2; PLC γ~2
产品上架时间：
2024-01-01
应用：
WB IHC
反应种属：
Human,Mouse
抗体类型：
Primary antibody
Swissprot：
P16885
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1180

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Rabbit polyclonal antibody to PLC γ2 (R747)

Description
Phosphoinositide~specific phospholipase C (PLC) plays a crucial role in the initiation of receptor mediated signal transduction through the generation of the two second messengers, inositol 1,4,5~triphosphate and diacylglycerol from phosphatidylinositol 4,5~bisphosphate. There are many mammalian PLC isozymes, including PLC β1, PLC β2, PLC β3, PLC β4, PLCγ1, PLCγ2, PLC δ1, PLC δ2 and PLCe. PLCδ exists as four different isoforms. PLC δ1, a calcium signal amplifier, is activated by an atypical GTP~binding protein. In addition, PLC δ1 is an effector for GTP~binding protein transglutaminase II~mediated oxytocin receptor and α1B~adrenoreceptor signaling. Mouse PLC δ1 is highly expressed in brain, heart, lung and testis.

Description

Phosphoinositide~specific phospholipase C (PLC) plays a crucial role in the initiation of receptor mediated signal transduction through the generation of the two second messengers, inositol 1,4,5~triphosphate and diacylglycerol from phosphatidylinositol 4,5~bisphosphate. There are many mammalian PLC isozymes, including PLC β1, PLC β2, PLC β3, PLC β4, PLCγ1, PLCγ2, PLC δ1, PLC δ2 and PLCe. PLCδ exists as four different isoforms. PLC δ1, a calcium signal amplifier, is activated by an atypical GTP~binding protein. In addition, PLC δ1 is an effector for GTP~binding protein transglutaminase II~mediated oxytocin receptor and α1B~adrenoreceptor signaling. Mouse PLC δ1 is highly expressed in brain, heart, lung and testis.

Specification
Aliases	1~phosphatidylinositol 4,5~bisphosphate phosphodiesterase gamma~2; Phosphoinositide phospholipase C~gamma~2; Phospholipase C~IV; PLC~IV; Phospholipase C~gamma~2; PLC~gamma~2; PLCG2; PLCγ2; PLC~γ2; PLC γ~2
Swissprot	P16885
clone	9C10E3
WB Predicted band size	~148kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	Synthetic peptide, corresponding to amino acids 720~770 of Human PLC γ2.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2