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Rabbit polyclonal antibody to p130 Cas (V404)

Western blot (WB) analysis of BCAR1 pAb at 1:500 dilution Lane1:A549 whole cell lysate(20ug) Lane2:Beas~2B whole cell lysate(40ug) Lane3:SGC7901 whole cell lysate(40ug) Lane4:PC12 whole cell lysate(40ug) Lane5:CT26 whole cell lysate(40ug)

Rabbit polyclonal antibody to p130 Cas (V404)

货号：
53323
别名：
Breast cancer anti~estrogen resistance protein 1; CRK~associated substrate; Cas scaffolding protein family member 1; p130cas; BCAR1; CAS; CASS1; CRKAS
产品上架时间：
2024-01-01
应用：
WB IHC
反应种属：
Human,Mouse
抗体类型：
Primary antibody
Swissprot：
P56945
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1180

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Rabbit polyclonal antibody to p130 Cas (V404)

Description
The p130Cas (Cas for Crk~associated substrate) is a common cellular target of phosphorylation signal via v~Crk and v~Src oncoproteins. p130Cas has a unique structure that contains a Src homology (SH)~3 domain followed by multiple YXXP motifs and a proline~rich regionp130Cas is implicated in a variety of biological processes including cell adhesion, cell migration, growth factor stimulation, cytokine receptor engagement and bacterial infection. Physiological functions of p130Cas include cardiovascular development, actin filament assembly and Src~induced cell transformation.

Description

The p130Cas (Cas for Crk~associated substrate) is a common cellular target of phosphorylation signal via v~Crk and v~Src oncoproteins. p130Cas has a unique structure that contains a Src homology (SH)~3 domain followed by multiple YXXP motifs and a proline~rich regionp130Cas is implicated in a variety of biological processes including cell adhesion, cell migration, growth factor stimulation, cytokine receptor engagement and bacterial infection. Physiological functions of p130Cas include cardiovascular development, actin filament assembly and Src~induced cell transformation.

Specification
Aliases	Breast cancer anti~estrogen resistance protein 1; CRK~associated substrate; Cas scaffolding protein family member 1; p130cas; BCAR1; CAS; CASS1; CRKAS
Swissprot	P56945
clone	5D6A10
WB Predicted band size	~130kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	Synthetic peptide, corresponding to amino acids 380~430 of Human p130 Cas.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2