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Rabbit polyclonal antibody to XRCC5 (D708)

Western blot (WB) analysis of XRCC5 (D708) pAb at 1:2000 dilution Lane1:MCF~7 whole cell lysate(40ug) Lane2:HCT116 whole cell lysate(40ug) Lane3:C6 whole cell lysate(40ug) Lane4:MEF whole cell lysate(40ug) Lane5:The Brain tissue lysate of Mouse(40ug)

Rabbit polyclonal antibody to XRCC5 (D708)

货号：
53319
别名：
X~ray repair cross~complementing protein 5; 86 kDa subunit of Ku antigen; ATP~dependent DNA helicase 2 subunit 2; ATP~dependent DNA helicase II 80 kDa subunit; CTC box~binding factor 85 kDa subunit; CTC85; CTCBF; DNA repair protein XRCC5; Ku80; Ku86; Ku~80; Ku~86; Lupus Ku autoantigen protein p86; Nuclear factor IV; Thyroid~lupus autoantigen; TLAA; X~ray repair complementing defective repair in Chinese hamster cells 5 (double~strand~break rejoining); XRCC5; G22P2
产品上架时间：
2024-01-01
应用：
WB IHC IF
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P13010
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1180

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Rabbit polyclonal antibody to XRCC5 (D708)

Description
XRCC5 encoded by this gene is the 80~kilodalton subunit of the Ku heterodimer protein which is also known as ATP~dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA~binding component of the DNA~dependent protein kinase, and it functions together with the DNA ligase IV~XRCC4 complex in the repair of DNA double~strand break by non~homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs~6, a mutant defective in DNA double~strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

Description

XRCC5 encoded by this gene is the 80~kilodalton subunit of the Ku heterodimer protein which is also known as ATP~dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA~binding component of the DNA~dependent protein kinase, and it functions together with the DNA ligase IV~XRCC4 complex in the repair of DNA double~strand break by non~homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs~6, a mutant defective in DNA double~strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

Specification
Aliases	X~ray repair cross~complementing protein 5; 86 kDa subunit of Ku antigen; ATP~dependent DNA helicase 2 subunit 2; ATP~dependent DNA helicase II 80 kDa subunit; CTC box~binding factor 85 kDa subunit; CTC85; CTCBF; DNA repair protein XRCC5; Ku80; Ku86; Ku~80; Ku~86; Lupus Ku autoantigen protein p86; Nuclear factor IV; Thyroid~lupus autoantigen; TLAA; X~ray repair complementing defective repair in Chinese hamster cells 5 (double~strand~break rejoining); XRCC5; G22P2
Swissprot	P13010
clone	2C3F3
WB Predicted band size	~82kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthetic peptide, corresponding to amino acids 680~720 of Human XRCC5.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2