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Rabbit polyclonal antibody to p15 INK4b (G113)

Western blot (WB) analysis of p15 INK4b (G113) polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:Raw264.7 whole cell lysate Lane3:H9C2 whole cell lysate

Rabbit polyclonal antibody to p15 INK4b (G113)

货号：
53270
别名：
Cyclin~dependent kinase 4 inhibitor B; Multiple tumor suppressor 2; MTS~2; p14~INK4b; p15~INK4b; P15ink4b; CDKN2B; MTS2
产品上架时间：
2024-01-01
应用：
WB IHC IF
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P42772
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1280

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Rabbit polyclonal antibody to p15 INK4b (G113)

Description
p15 (PAF), also known as PAF, L5, OEATC1 (overexpressed in anaplastic thyroid carcinoma 1) or NS5ATP9, is a 111 amino acid protein that localizes to both the nucleus and the mitochondria. Highly expressed in colon and thymus with lower expression in liver, ovary, kidney, spleen, placenta and small intestine, p15 (PAF) interacts with the nuclear antigen PCNA and, through this interaction, is thought to protect cells from UV~induced cell death. The association of p15 (PAF) and PCNA is enhanced by UV treatment and is facilitated by the binding of ING1, a tumor suppressor that can induce apoptosis.

Description

p15 (PAF), also known as PAF, L5, OEATC1 (overexpressed in anaplastic thyroid carcinoma 1) or NS5ATP9, is a 111 amino acid protein that localizes to both the nucleus and the mitochondria. Highly expressed in colon and thymus with lower expression in liver, ovary, kidney, spleen, placenta and small intestine, p15 (PAF) interacts with the nuclear antigen PCNA and, through this interaction, is thought to protect cells from UV~induced cell death. The association of p15 (PAF) and PCNA is enhanced by UV treatment and is facilitated by the binding of ING1, a tumor suppressor that can induce apoptosis.

Specification
Aliases	Cyclin~dependent kinase 4 inhibitor B; Multiple tumor suppressor 2; MTS~2; p14~INK4b; p15~INK4b; P15ink4b; CDKN2B; MTS2
Swissprot	P42772
clone	10G3E10
WB Predicted band size	~15kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthetic peptide, corresponding to amino acids 100~150 of Human p15 INK4b.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2