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Rabbit polyclonal antibody to Cytokeratin 5 (S573)

Western blot (WB) analysis of Cytokeratin 5 (S573) polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate(40ug) Lane2:PC12 whole cell lysate(40ug) Lane3:NIH~3T3 whole cell lysate(40ug)

Rabbit polyclonal antibody to Cytokeratin 5 (S573)

货号：
53254
别名：
Keratin, type II cytoskeletal 5; 58 kDa cytokeratin; Cytokeratin~5; Cytokeratin5; Short name=CK~5; CK5; Keratin~5; Keratin5; Keratin 5; Short name=K5; Type~II keratin Kb5; KRT5
产品上架时间：
2024-01-01
应用：
WB IHC IF
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P13647
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1280

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Rabbit polyclonal antibody to Cytokeratin 5 (S573)

Description
Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non~keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation which is directly applicable to the characterization of malignant tumors. Cytokeratin 5 is expressed in normal basal cells. Mutations of the Cytokeratin 5 gene (KRT5) have been shown to result in the autosomal dominant disorder epidermolysis bullosa (EB).

Description

Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non~keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation which is directly applicable to the characterization of malignant tumors. Cytokeratin 5 is expressed in normal basal cells. Mutations of the Cytokeratin 5 gene (KRT5) have been shown to result in the autosomal dominant disorder epidermolysis bullosa (EB).

Specification
Aliases	Keratin, type II cytoskeletal 5; 58 kDa cytokeratin; Cytokeratin~5; Cytokeratin5; Short name=CK~5; CK5; Keratin~5; Keratin5; Keratin 5; Short name=K5; Type~II keratin Kb5; KRT5
Swissprot	P13647
clone	9C1A8
WB Predicted band size	~62kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthetic peptide, corresponding to amino acids 550~600 of Human Cytokeratin 5.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2