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Rabbit polyclonal antibody to Galectin~3 (N174)

Western blot (WB) analysis of Galectin~3 (N174) polyclonal antibody at 1:500 dilution Lane1:THP~1 whole cell lysate(40ug) Lane2:L02 whole cell lysate(40ug) Lane3:HCT116 whole cell lysate(40ug) Lane4:HepG2 whole cell lysate(40ug)

Rabbit polyclonal antibody to Galectin~3 (N174)

货号：
53225
别名：
CBP35; Gal~3; 35 kDa lectin; Carbohydrate~binding protein 35; CBP 35; Galactose~specific lectin 3; Galactoside~binding protein; GALBP; IgE~binding protein; Laminin~binding protein; Lectin L~29; Mac~2 antigen; LGALS3; MAC2; Galectin 3; Galectin3
产品上架时间：
2024-01-01
应用：
WB IHC IF
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P17931
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1280

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Rabbit polyclonal antibody to Galectin~3 (N174)

Description
The galectin~3 protein, also known as Mac~2, hMac~2, GALBP, CBP35 or LGALS3, contains a single carbohydrate binding domain, which binds galactose~containing glycoconjugates. galectin~3 is expressed in colonic and intestinal epithelium, inflammatory macrophages, papillary and follicular carcinomas, neoplastic astrocytes and some B and T lymphocytes. Upregulated expression of galectin~3 is involved in cancer progression and metastasis. galectin~3 mediates the endocytosis of β~1 Integrins in a lactose~dependant manner and is associated with thyroid malignancy and Crohn’s disease. It may also be used as a marker for diagnosing cases involving Hurthle cell adenomas and carcinomas.

Description

The galectin~3 protein, also known as Mac~2, hMac~2, GALBP, CBP35 or LGALS3, contains a single carbohydrate binding domain, which binds galactose~containing glycoconjugates. galectin~3 is expressed in colonic and intestinal epithelium, inflammatory macrophages, papillary and follicular carcinomas, neoplastic astrocytes and some B and T lymphocytes. Upregulated expression of galectin~3 is involved in cancer progression and metastasis. galectin~3 mediates the endocytosis of β~1 Integrins in a lactose~dependant manner and is associated with thyroid malignancy and Crohn’s disease. It may also be used as a marker for diagnosing cases involving Hurthle cell adenomas and carcinomas.

Specification
Aliases	CBP35; Gal~3; 35 kDa lectin; Carbohydrate~binding protein 35; CBP 35; Galactose~specific lectin 3; Galactoside~binding protein; GALBP; IgE~binding protein; Laminin~binding protein; Lectin L~29; Mac~2 antigen; LGALS3; MAC2; Galectin 3; Galectin3
Swissprot	P17931
clone	4H3E4
WB Predicted band size	~30kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthetic peptide, corresponding to amino acids 140~190 of Human Galectin~3.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2