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Rabbit polyclonal antibody to DNA~PKCS (R4090)

Western blot (WB) analysis of DNA~PKCS (R4090) pAb at 1:500 dilution Lane1:MCF~7 whole cell lysate(15ug) Lane2:A549 whole cell lysate(15ug) Lane3:CT26 whole cell lysate(40ug) Lane4:The Lung tissue lysate of Rat(40ug)

Rabbit polyclonal antibody to DNA~PKCS (R4090)

货号：
53213
别名：
DNA~dependent protein kinase catalytic subunit; DNA~PK catalytic subunit; DNA~PKcs; DNPK1; p460; PRKDC; HYRC; HYRC1
产品上架时间：
2024-01-01
应用：
WB IHC IF
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P78527
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1280

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Rabbit polyclonal antibody to DNA~PKCS (R4090)

Description
The phosphatidylinositol kinase (PIK) family members fall into two distinct subgroups. The first subgroup contains proteins such as the PI 3~ and PI 4~kinases and the second group comprises the PIK~related kinases. The PIK~related kinases include Atm, DNA~PKCS and FRAP. These proteins have in common a region of homology at their carboxy termini that is not present in the PI 3~ and PI 4~kinases. All of the members of the PIK~related kinases are also over 270 kDa. The Atm gene is mutated in the autosomal recessive disorder ataxia telangiectasia (AT) that is characterized by cerebellar degeneration (ataxia) and the appearance of dilated blood vessels (telangiectases) in the conjunctivae of the eyes.

Description

The phosphatidylinositol kinase (PIK) family members fall into two distinct subgroups. The first subgroup contains proteins such as the PI 3~ and PI 4~kinases and the second group comprises the PIK~related kinases. The PIK~related kinases include Atm, DNA~PKCS and FRAP. These proteins have in common a region of homology at their carboxy termini that is not present in the PI 3~ and PI 4~kinases. All of the members of the PIK~related kinases are also over 270 kDa. The Atm gene is mutated in the autosomal recessive disorder ataxia telangiectasia (AT) that is characterized by cerebellar degeneration (ataxia) and the appearance of dilated blood vessels (telangiectases) in the conjunctivae of the eyes.

Specification
Aliases	DNA~dependent protein kinase catalytic subunit; DNA~PK catalytic subunit; DNA~PKcs; DNPK1; p460; PRKDC; HYRC; HYRC1
Swissprot	P78527
clone	5G4F10
WB Predicted band size	~450kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthetic peptide, corresponding to amino acids 4060~4110 of Human DNA~PKCS.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2