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Rabbit polyclonal antibody to SQSTM1
Western blot (WB) analysis of SQSTM1 polyclonal antibody at 1:500 dillution Lane1:Hela whole cell lysate(40μg) Lane2:NIH~3T3 whole cell lysate(30μg) Lane3:PC12 whole cell lysate(40μg)
Rabbit polyclonal antibody to SQSTM1

Rabbit polyclonal antibody to SQSTM1

  • 货号:

    53164
  • 别名:

    Sequestosome~1; EBI3~associated protein of 60 kDa; EBIAP; p60; Phosphotyrosine~independent ligand for the Lck SH2 domain of 62 kDa; Ubiquitin~binding protein p62; SQSTM1; ORCA; OSIL
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB IHC IP IF
  • 反应种属:

    Human,Mouse,Rat
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q13501
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥1280

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Rabbit polyclonal antibody to SQSTM1

Description

The chronic focal skeletal disorder, Paget’s disease of bone, affects 2~3% of the population over the age of 60 years. Paget’s disease is characterized by increased bone resorption by osteoclasts, followed by abundant new bone formation that is of poor quality. The disease leads to several complications including bone pain and deformities, as well as fissures and fractures. Mutations in the ubiquitin~associated (UBA) domain of the Sequestosome 1 protein (SQSTM1), also designated p62 or ZIP, commonly cause Paget’s disease since the UBA is necessary for aggregate sequestration and cell survival.

Specification

Aliases Sequestosome~1; EBI3~associated protein of 60 kDa; EBIAP; p60; Phosphotyrosine~independent ligand for the Lck SH2 domain of 62 kDa; Ubiquitin~binding protein p62; SQSTM1; ORCA; OSIL
Swissprot Q13501
clone 9E3B6
WB Predicted band size ~60kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen Recombinant full length Human SQSTM1.
Formulation 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Application

WB 1/500~1/1000
IP 1/50~1/200
IHC 1/50~1/200
IF/ICC 1/50~1/200

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#53164