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Rabbit polyclonal antibody to SQSTM1
-
货号:
53164 -
别名:
Sequestosome~1; EBI3~associated protein of 60 kDa; EBIAP; p60; Phosphotyrosine~independent ligand for the Lck SH2 domain of 62 kDa; Ubiquitin~binding protein p62; SQSTM1; ORCA; OSIL -
应用:
WB IHC IP IF -
反应种属:
Human,Mouse,Rat -
抗体类型:
Primary antibody -
Swissprot:
Q13501 -
规格:
-
数量:
-+ -
说明书:
目录价¥1280
Rabbit polyclonal antibody to SQSTM1
Description |
|---|
The chronic focal skeletal disorder, Paget’s disease of bone, affects 2~3% of the population over the age of 60 years. Paget’s disease is characterized by increased bone resorption by osteoclasts, followed by abundant new bone formation that is of poor quality. The disease leads to several complications including bone pain and deformities, as well as fissures and fractures. Mutations in the ubiquitin~associated (UBA) domain of the Sequestosome 1 protein (SQSTM1), also designated p62 or ZIP, commonly cause Paget’s disease since the UBA is necessary for aggregate sequestration and cell survival. |
Specification |
|
|---|---|
| Aliases | Sequestosome~1; EBI3~associated protein of 60 kDa; EBIAP; p60; Phosphotyrosine~independent ligand for the Lck SH2 domain of 62 kDa; Ubiquitin~binding protein p62; SQSTM1; ORCA; OSIL |
| Swissprot | Q13501 |
| clone | 9E3B6 |
| WB Predicted band size | ~60kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant full length Human SQSTM1. |
| Formulation | 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 |
Application |
|
|---|---|
| WB | 1/500~1/1000 |
| IP | 1/50~1/200 |
| IHC | 1/50~1/200 |
| IF/ICC | 1/50~1/200 |
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#53164
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