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Rabbit polyclonal antibody to ULK1 (phospho~Ser555)

Western blot (WB) analysis of PIK3C3/VPS34 (Phospho~Ser249) polyclonal antibody at 1:500 dilution Lane1:LO2 treated with PBS(1×,PH7.4) for 1 hour then treated with DMEM(10%FBS) for 15 minutes whole cell lysate Lane2:LO2 treated with PBS(1×,PH7.4) for 1 hour then treated with DMEM(10%FBS) for 5 minutes whole cell lysate Lane3:LO2 treated with PBS(1×,PH7.4) for 1 hour whole cell lysate Lane4:LO2 whole cell lysate

Rabbit polyclonal antibody to ULK1 (phospho~Ser555)

货号：
53160
别名：
Serine/threonine~protein kinase ULK1; Autophagy~related protein 1 homolog; ATG1; Unc~51~like kinase 1; ULK1; KIAA0722
产品上架时间：
2024-01-01
应用：
WB
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
O75385
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1280

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Rabbit polyclonal antibody to ULK1 (phospho~Ser555)

Description
ULK1 and ULK2 (for UNC~51~like kinase) encode similar amino~terminal serine/threonine kinase domains, a proline/serine~rich (PS) domain, and a species conserved carboxyl~terminal domain. Both share homology with the UNC~51 kinase from Caenorhabditis elegans and the APG1 kinase in yeast, which are involved in axonal extension and growth, and autophagy, respectively. ULK1 and ULK2 are thought to auto~phosphorylate the PS domain in vitro, and the significant homology among vertebrates suggest that ULK1 and ULK2 are involved in the regulation of fundamental biological processes.

Description

ULK1 and ULK2 (for UNC~51~like kinase) encode similar amino~terminal serine/threonine kinase domains, a proline/serine~rich (PS) domain, and a species conserved carboxyl~terminal domain. Both share homology with the UNC~51 kinase from Caenorhabditis elegans and the APG1 kinase in yeast, which are involved in axonal extension and growth, and autophagy, respectively. ULK1 and ULK2 are thought to auto~phosphorylate the PS domain in vitro, and the significant homology among vertebrates suggest that ULK1 and ULK2 are involved in the regulation of fundamental biological processes.

Specification
Aliases	Serine/threonine~protein kinase ULK1; Autophagy~related protein 1 homolog; ATG1; Unc~51~like kinase 1; ULK1; KIAA0722
Swissprot	O75385
clone	10E1A10
WB Predicted band size	~150kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthetic phosphopeptide derived from human ULK1 around the phosphorylation site of Ser555.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2