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Western blot (WB) analysis of PIK3C3/VPS34 pAb at 1:500 dilution Lane1:C6 whole cell lysate(40ug) Lane2:AML~12 whole cell lysate(40ug) Lane3:H1792 whole cell lysate(40ug) Lane4:MCF~7 whole cell lysate(40ug)

Rabbit polyclonal antibody to VPS34

货号：
53156
别名：
Phosphatidylinositol 3~kinase catalytic subunit type 3 (EC:2.7.1.137); PI3~kinase type 3; PI3K type 3; PtdIns~3~kinase type 3; Phosphatidylinositol 3~kinase p100 subunit; Phosphoinositide~3~kinase class 3; hVps34; PIK3C3;
产品上架时间：
2024-01-01
应用：
WB
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
Q8NEB9
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1280

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Rabbit polyclonal antibody to VPS34

Description
VPS34 (vacuolar protein sorting~associated protein 34), also known as VPT29, VPL7, PEP15 or END12, is a 875 amino acid peripheral membrane protein that localizes to the golgi apparatus. Belonging to the PI3/PI4~kinase family, VPS34 is involved in endosome~to~Golgi retrograde transport as part of the VPS34 PI3~kinase complex II. The VPS34 PI3~kinase complex II is required for the endosome~to~Golgi retrieval of PEP1 and KEX2, and the recruitment of VPS5 and VPS7, two components of the retromer complex, to endosomal membranes. It has been suggested that VPS34 may also be involved in ethanol tolerance and cell wall integrity.

Description

VPS34 (vacuolar protein sorting~associated protein 34), also known as VPT29, VPL7, PEP15 or END12, is a 875 amino acid peripheral membrane protein that localizes to the golgi apparatus. Belonging to the PI3/PI4~kinase family, VPS34 is involved in endosome~to~Golgi retrograde transport as part of the VPS34 PI3~kinase complex II. The VPS34 PI3~kinase complex II is required for the endosome~to~Golgi retrieval of PEP1 and KEX2, and the recruitment of VPS5 and VPS7, two components of the retromer complex, to endosomal membranes. It has been suggested that VPS34 may also be involved in ethanol tolerance and cell wall integrity.

Specification
Aliases	Phosphatidylinositol 3~kinase catalytic subunit type 3 (EC:2.7.1.137); PI3~kinase type 3; PI3K type 3; PtdIns~3~kinase type 3; Phosphatidylinositol 3~kinase p100 subunit; Phosphoinositide~3~kinase class 3; hVps34; PIK3C3;
Swissprot	Q8NEB9
clone	3G9B3
WB Predicted band size	~100kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthetic phosphopeptide derived from human VPS34 around the phosphorylation site of Ser249.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2