搜索

热搜关键词：
P16
IRAK4
GPC3
MMP9
IL28A
EPCAM
MK167
HAS2

请登录

提醒成功

QQ登录

微信登录

同意并阅读使用条款和隐私策略

账号密码登录

微信/QQ登录

没有账号？立即注册

搜索

抗体销售咨询健康评估咨询 mRNA-LNP咨询

0731-88388785

首页 > 产品中心 > 产品详情

Rabbit polyclonal antibody to Bcl~2 (P65)

Western blot (WB) analysis of Bcl~2 (P65) polyclonal antibody at 1:1000 dilution Lane1:The Kidney tissue lysate of Rat(30ug) Lane2:The Heart tissue lysate of Mouse(30ug)

Rabbit polyclonal antibody to Bcl~2 (P65)

货号：
53058
别名：
Bcl~2 homologous antagonist/killer; Apoptosis regulator BAK; Bcl~2~like protein 7; Bcl2~L~7; BAK1; BAK; BCL2L7; CDN1
产品上架时间：
2024-01-01
应用：
WB
反应种属：
Human, Mouse, Rat
抗体类型：
Primary antibody
Swissprot：
Q16611
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1280

分享
咨询
收藏

加入购物车

立即购买

Rabbit polyclonal antibody to Bcl~2 (P65)

Description
Bak is a proapoptotic member of the Bcl~2 family. This protein is located on the outer membrane of mitochondria and is an essential component for transduction of apoptotic signals through the mitochondrial pathway. Upon apoptotic stimulation, an upstream stimulator like truncated BID (tBID) induces conformational changes in Bak to form oligomer channels in the mitochondrial membrane for cytochrome c release. The release of cytochrome c to the cytosol activates the caspase~9 pathway and eventually leads to cell death.

Description

Bak is a proapoptotic member of the Bcl~2 family. This protein is located on the outer membrane of mitochondria and is an essential component for transduction of apoptotic signals through the mitochondrial pathway. Upon apoptotic stimulation, an upstream stimulator like truncated BID (tBID) induces conformational changes in Bak to form oligomer channels in the mitochondrial membrane for cytochrome c release. The release of cytochrome c to the cytosol activates the caspase~9 pathway and eventually leads to cell death.

Specification
Aliases	Bcl~2 homologous antagonist/killer; Apoptosis regulator BAK; Bcl~2~like protein 7; Bcl2~L~7; BAK1; BAK; BCL2L7; CDN1
Swissprot	Q16611
clone	7F5C8
WB Predicted band size	~30kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	Synthetic peptide, corresponding to Human Bcl~2.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.