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Western blot (WB) analysis of Caspase~3 (D146) polyclonal antibody at 1:500 dilution
Lane1:MCF~7 whole cell lysate(30ug)
Lane2:L02 whole cell lysate(30ug)
Rabbit polyclonal antibody to Caspase~3 (D146)
-
货号：
53057 -
别名：
Caspase~3; CASP~3; Apopain; Cysteine protease CPP32; CPP~32; Protein Yama; SREBP cleavage activity 1; SCA~1; Caspase~3 subunit p17; Caspase~3 subunit p12; CASP3; CPP32 -
应用：
WB IF -
反应种属：
Human -
抗体类型：
Primary antibody -
Swissprot：
P42574 -
规格：
-
数量：
-+ -
说明书：
目录价¥1280
Rabbit polyclonal antibody to Caspase~3 (D146)
Description |
|---|
Caspase~3 (CPP~32, Apopain, Yama, SCA~1) is a critical executioner of apoptosis, as it is either partially or totally responsible for the proteolytic cleavage of many key proteins, such as the nuclear enzyme poly (ADP~ribose) polymerase (PARP). Activation of caspase~3 requires proteolytic processing of its inactive zymogen into activated p17 and p12 fragments. Cleavage of caspase~3 requires the aspartic acid residue at the P1 position. |
Specification |
|
|---|---|
| Aliases | Caspase~3; CASP~3; Apopain; Cysteine protease CPP32; CPP~32; Protein Yama; SREBP cleavage activity 1; SCA~1; Caspase~3 subunit p17; Caspase~3 subunit p12; CASP3; CPP32 |
| Swissprot | P42574 |
| clone | 1B3D6 |
| WB Predicted band size | ~33kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthetic peptide, corresponding to Human Caspase~3. |
| Formulation | 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2. |
Application |
|
|---|---|
| WB | 1/500~1/1000 |
| IF/ICC | 1/50~200 |
For Reseach Only
Application Key：WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#53057
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