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Rabbit polyclonal antibody to Caspase~3 (Phospho~S150)

Western blot (WB) analysis of Caspase~3 (Phospho~S150) polyclonal antibody at 1:1000 dilution Lane1:Jurkat whole cell lysate(30ug) Lane2:Jurkat treated with λ~phosphatase whole cell lysate(30ug)

Rabbit polyclonal antibody to Caspase~3 (Phospho~S150)

货号：
53035
别名：
Caspase~3; CASP~3; Apopain; Cysteine protease CPP32; CPP~32; Protein Yama; SREBP cleavage activity 1; SCA~1; Caspase~3 subunit p17; Caspase~3 subunit p12; CASP3; CPP32
产品上架时间：
2024-01-01
应用：
WB
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P42574
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1180

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Rabbit polyclonal antibody to Caspase~3 (Phospho~S150)

Description
Caspase~3 (CPP~32, Apopain, Yama, SCA~1) is a critical executioner of apoptosis, as it is either partially or totally responsible for the proteolytic cleavage of many key proteins, such as the nuclear enzyme poly (ADP~ribose) polymerase (PARP). Activation of caspase~3 requires proteolytic processing of its inactive zymogen into activated p17 and p12 fragments. Cleavage of caspase~3 requires the aspartic acid residue at the P1 position.

Description

Caspase~3 (CPP~32, Apopain, Yama, SCA~1) is a critical executioner of apoptosis, as it is either partially or totally responsible for the proteolytic cleavage of many key proteins, such as the nuclear enzyme poly (ADP~ribose) polymerase (PARP). Activation of caspase~3 requires proteolytic processing of its inactive zymogen into activated p17 and p12 fragments. Cleavage of caspase~3 requires the aspartic acid residue at the P1 position.

Specification
Aliases	Caspase~3; CASP~3; Apopain; Cysteine protease CPP32; CPP~32; Protein Yama; SREBP cleavage activity 1; SCA~1; Caspase~3 subunit p17; Caspase~3 subunit p12; CASP3; CPP32
Swissprot	P42574
clone	4B7D2
WB Predicted band size	~33kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human
Immunogen	Synthetic phosphopeptide derived from human Caspase~3 around the phosphorylation site of Serine 150.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.