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Western blot (WB) analysis of LYVE1 pAb at 1:500 dilution Lane1:CT26 whole cell lysate(40ug) Lane2:C6 whole cell lysate(40ug) Lane3:HCT116 whole cell lysate(40ug) Lane4:MCF~7 whole cell lysate(40ug) Lane5:SGC7901 whole cell lysate(40ug)

Rabbit polyclonal antibody to LYVE1

货号：
53001
别名：
Cell surface retention sequence~binding protein 1; CRSBP 1; CRSBP~1; CRSBP1; extracellular link domain containing 1; extracellular link domain~containing 1; Extracellular link domain~containing protein 1; HAR; hyaluronic acid receptor; Lymphatic endothelium specific hyaluronan receptor; lymphatic vessel endothelial hyaluronan receptor 1; Lymphatic vessel endothelial hyaluronic acid receptor 1; LYVE 1; LYVE~1; LYVE1; LYVE1; XLKD1;
产品上架时间：
2024-01-01
应用：
WB
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
Q9Y5Y7
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1280

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Rabbit polyclonal antibody to LYVE1

Description
Recently a number of interesting molecules have been identified that may be exploited as markers for lymphatic endothelium, including the hyaluronan receptor LYVE1, PALE, VEGFR3, podoplanin. LYVE1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE1 predicts a 322~residue type I integral membrane polypeptide 41% similar to the CD44 HA receptor with a 212~residue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE1 molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE1 molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels.

Description

Recently a number of interesting molecules have been identified that may be exploited as markers for lymphatic endothelium, including the hyaluronan receptor LYVE1, PALE, VEGFR3, podoplanin. LYVE1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE1 predicts a 322~residue type I integral membrane polypeptide 41% similar to the CD44 HA receptor with a 212~residue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE1 molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE1 molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels.

Specification
Aliases	Cell surface retention sequence~binding protein 1; CRSBP 1; CRSBP~1; CRSBP1; extracellular link domain containing 1; extracellular link domain~containing 1; Extracellular link domain~containing protein 1; HAR; hyaluronic acid receptor; Lymphatic endothelium specific hyaluronan receptor; lymphatic vessel endothelial hyaluronan receptor 1; Lymphatic vessel endothelial hyaluronic acid receptor 1; LYVE 1; LYVE~1; LYVE1; LYVE1; XLKD1;
Swissprot	Q9Y5Y7
clone	6F2H7
WB Predicted band size	36kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthetic peptide, corresponding to amino acids 60~110 of Human LYVE~1.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2