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Western blot analysis of GSDMD in 3T3 lysates using GSDMD antibody.

Rabbit Monoclonal Antibody to GSDMD

  • 货号:

    P23650
  • 别名:

    Gsdmd;Gsdmdc1;Gasdermin-D ;Gasdermin domain-containing protein 1
  • 产品上架时间:

    2024-07-16
  • 应用:

    WB,IHC-P
  • 反应种属:

    Mouse,Rat
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q9D8T2
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Rabbit Monoclonal Antibody to GSDMD

Description

Gasdermin-D,Precursor of a pore-forming protein that plays a key role in host defense against pathogen infection and danger signals (PubMed:26375003, PubMed:26375259, PubMed:27281216). This form constitutes the precursor of the pore-forming protein: upon cleavage, the released N-terminal moiety (Gasdermin-D, N-terminal) binds to membranes and forms pores, triggering pyroptosis (PubMed:26375003, PubMed:26375259, PubMed:27281216).

Specification

Aliases Gsdmd;Gsdmdc1;Gasdermin-D ;Gasdermin domain-containing protein 1
Entrez GeneID 69146
Swissprot Q9D8T2
clone 6D4
WB Predicted band size 53kd
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Mouse,Rat
Immunogen Recombinant protein of mouse GSDMD
Formulation 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.

Application

WB 1/500-1/1000
IHC 1/50-1/100

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#P23650