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Western blot analysis of extract from MCF-7, 293, HepG2 cells using ABL1/2 (Ab-393/439) Antibody P41554.

Rabbit Polyclonal Antibody to ABL1/2 (Ab-393/439)

  • 货号:

    P41554
  • 别名:

    ABL; v-abl; c-ABL; p150; JTK7
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB
  • 反应种属:

    Human,Mouse
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P00519
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥1980

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Rabbit Polyclonal Antibody to ABL1/2 (Ab-393/439)

Description

Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks.

References

Wang, J.Y. et al. (2000) Oncogene 19, 5643-5650. Danial, N.N. et al. (2000) Oncogene 19, 2523-2531. Brasher, B.B. et al. (2000) J. Biol. Chem. 275, 35631-35637. Pluk, H. et al. (2002) Cell 108, 247-259.

Specification

Aliases ABL; v-abl; c-ABL; p150; JTK7
Entrez GeneID 25;
Swissprot P00519
WB Predicted band size 135 210kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse
Immunogen Peptide sequence around aa.391~395/437~441(D-T-Y-T-A) derived from Human ABL1/2.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/1000

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#P41554