Rabbit Polyclonal Antibody to PI3 Kinase p85/p55(Ab-467/199)

Description
PI3K binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues.

References
Stoyanov, B. et al. (1995) Science 269, 690-3. Simpson, L. and Parsons, R. (2001) Exp Cell Res 264, 29-41. Neri, L.M. et al. (2002) Biochim Biophys Acta 1584, 73-80.

Specification
Aliases	p85, AGM7, p85-ALPHA, p55, p55-GAMMA
Entrez GeneID	5295;
Swissprot	P27986
WB Predicted band size	55, 85kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around aa.465~469(L-Y-E-E-Y) derived from Human PI3 Kinase p85/p55.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Application
IHC	1/50-1/100