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Mouse Monoclonal Antibody to PARL

  • 货号:

    20241
  • 别名:

    PSARL; PSARL1; RHBDS1
  • 产品上架时间:

    2024-01-01
  • 应用:

  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q9H300
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to PARL

Description

PARL: presenilin associated, rhomboid-like. This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms.

References

1. J Alzheimers Dis. 2001 Apr;3(2):181-190.
2. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903.
3. Nature. 2003 May 29;423(6939):537-41.

Specification

Aliases PSARL; PSARL1; RHBDS1
Entrez GeneID 55486
Swissprot Q9H300
clone 8C4B2
Host/Isotype Mouse IgG2b
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of PARL (aa112-167) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

ELISA 1/10000

Product Image

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#20241