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Western blot analysis using EphB4 mouse mAb against Jurkat (1) and HEK293 (2) cell lysate.
HOT

Mouse Monoclonal Antibody to EphB4

  • 货号:

    20221
  • 别名:

    HTK; MYK1; TYRO11
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P54760
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to EphB4

Description

EphB4: EPH receptor B4. Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development.

References

1. Biochem Biophys Res Commun. 2004 Aug 27;321(3):681-7.
2. Cancer Res. 2005 Jun 1;65(11):4623-32.
3. Development. 2005 Sep;132(18):4097-106.

Specification

Aliases HTK; MYK1; TYRO11
Entrez GeneID 2050
Swissprot P54760
clone 7H4A6
WB Predicted band size 108kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of EphB4 (aa562-612)expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500 - 1/2000
ELISA 1/10000

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#20221