提醒成功

搜索
Rabbit Polyclonal Antibody to Amyloid-β (phospho Thr743)
-
货号:
P44644 -
别名:
APP; A4; AD1; Amyloid beta A4 protein; ABPP; APPI; APP; Alzheimer disease amyloid protein; Cerebral vascular amyloid peptide; CVAP; PreA4; Protease nexin-II; PN-II -
应用:
WB,IHC,IF -
反应种属:
Human,Mouse,Rat -
抗体类型:
Primary antibody -
Swissprot:
P05067 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180

Rabbit Polyclonal Antibody to Amyloid-β (phospho Thr743)
Description |
---|
amyloid beta precursor protein(APP) Homo sapiens This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Aug 2014], |
Specification |
|
---|---|
Aliases | APP; A4; AD1; Amyloid beta A4 protein; ABPP; APPI; APP; Alzheimer disease amyloid protein; Cerebral vascular amyloid peptide; CVAP; PreA4; Protease nexin-II; PN-II |
Entrez GeneID | 351 |
Swissprot | P05067 |
WB Predicted band size | 140kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Rat |
Immunogen | The antiserum was produced against synthesized peptide derived from human Amyloid beta A4 around the phosphorylation site of Thr743/668. AA range:711-760 |
Formulation | Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol. |
Application |
|
---|---|
WB | 1/500 - 1/2000 |
IHC | 1/100 - 1/300 |
IF | 1/200 - 1/1000 |
ELISA | 1/10000 |
Product Image
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#P44644

相关产品


