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Gel: 12%SDS-PAGE, Lysate: 40 ug, Lane: Human plasma solution, Primary antibody:47276(HBG1/HBG2 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds

The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 47276(HBG1/HBG2 Antibody) at dilution 1/100.(Original magnification: 200)

The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using 47276(HBG1/HBG2 Antibody) at dilution 1/100.(Original magnification: 200)

Rabbit Polyclonal Antibody to HBG1/HBG2

货号：
P43575
别名：
fetal hemoglobin; HBGA; HBGR; HBG-T2; HSGGL1; PRO2979; TNCY; HBG-T1
产品上架时间：
2024-01-01
应用：
WB,IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P69891
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to HBG1/HBG2

Description
The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.

Description

The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.

Specification
Aliases	fetal hemoglobin; HBGA; HBGR; HBG-T2; HSGGL1; PRO2979; TNCY; HBG-T1
Entrez GeneID	3047;
Swissprot	P69891
WB Predicted band size	16kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Fusion protein of human HBG1/HBG2
Formulation	Purified antibody in PBS with 0.05% sodium azide.