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Western blot analysis using EI2BG mouse mAb against K562 (1), Hela (2),MCF-7 (3) and HL-60 (4) cell lysate.

Immunofluorescence analysis of Hela cells using EI2BG mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)

Flow cytometric analysis of HL-60 cells using EI2BG mouse mAb (green) and negative control (red).

Immunohistochemical analysis of paraffin-embedded human liver tissues using EI2BG mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded human kidney tissues using EI2BG mouse mAb with DAB staining.

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Mouse Monoclonal Antibody to EI2BG

货号：
32387
别名：
EIF2B3;EIF-2B; EIF2Bgamma
产品上架时间：
2024-01-01
应用：
WB,IHC,IF,FCM
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q9NR50
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Mouse Monoclonal Antibody to EI2BG

Description
The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Description

The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

References
1.Brain Dev. 2016 May;38(5):507-15. 2.PLoS One. 2015 Mar 11;10(3):e0118001.

Specification
Aliases	EIF2B3;EIF-2B; EIF2Bgamma
Entrez GeneID	8891
Swissprot	Q9NR50
clone	1B9C12
WB Predicted band size	50.2kDa
Host/Isotype	Mouse IgG1
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Purified recombinant fragment of human EI2BG expressed in E. Coli.
Formulation	Purified antibody in PBS with 0.05% sodium azide