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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Flow cytometric analysis of HEK293 cells using SH2B2 mouse mAb (green) and negative control (red).
Flow cytometric analysis of HepG2 cells using SH2B2 mouse mAb (green) and negative control (red).
Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues using SH2B2 mouse mAb with DAB staining.
Immunohistochemical analysis of paraffin-embedded human colon cancer tissues using SH2B2 mouse mAb with DAB staining.
HOT

Mouse Monoclonal Antibody to SH2B2

  • 货号:

    32372
  • 别名:

    APS
  • 产品上架时间:

    2024-01-01
  • 应用:

    IHC,FCM
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    O14492
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to SH2B2

Description

The protein encoded by this gene is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine-phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc/Grb2 pathway.

References

1.Cancer Epidemiol Biomarkers Prev. 2002 Jul;11(7):664-9.
2.J Biol Chem. 2005 May 13;280(19):18943-9.

Specification

Aliases APS
Entrez GeneID 10603
Swissprot O14492
clone 5E11G7
WB Predicted band size 67.7kDa
Host/Isotype Mouse IgG2b
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human SH2B2 (AA: 497-676) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

IHC 1/200 - 1/1000
FCM 1/200 - 1/400
ELISA 1/10000