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Mouse Monoclonal Antibody to Glucose-6-phosphate isomerase
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货号:
20198 -
别名:
AMF; NLK; PGI; PHI; GNPI; SA-36; GPI -
应用:
WB,IHC,IF -
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
P06744 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180

Mouse Monoclonal Antibody to Glucose-6-phosphate isomerase
Description |
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Glucose-6-phosphate isomerase, or phosphoglucose isomerase, also known as GPI. It belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways and it is an enzyme that catalyzes the conversion of glucose-6-phosphate into fructose 6-phosphate in the second step of glycolysis. The protein functions in different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in GPI are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment. |
References |
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1. Biochem Biophys Res Commun. 2004 Oct 15;323(2):518-22. 2. Biochem Biophys Res Commun. 2006 Oct 20;349(2):838-45. 3. Hum Mutat. 2006 Nov;27(11):1159. 4. Leuk Lymphoma. 2006 Oct;47(10):2234-43. |
Specification |
|
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Aliases | AMF; NLK; PGI; PHI; GNPI; SA-36; GPI |
Entrez GeneID | 2821 |
Swissprot | P06744 |
clone | 1B7D7 |
WB Predicted band size | 63kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human GPI expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
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IHC | 1/200 - 1/1000 |
IF | 1/200 - 1/1000 |
ELISA | 1/10000 |
Product Image
- Western blot analysis using GPI mouse mAb against HepG2 (1) , SMMC-7721 (2) cell lysate and rat liver tissues lysate (3).
- Confocal Immunofluorescence analysis of L-02 cells using GPI mouse mAb (green). Red: Actin filaments have been labeled with DY-554 phalloidin. Blue: DRAQ5 fluorescent DNA dye.
- Immunohistochemical analysis of paraffin-embedded human Kidney tissues using GPI mouse mAb.
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#20198

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