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Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using P42833 at dilution 1/50.
Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissue using P42833 at dilution 1/50.

Rabbit Polyclonal Antibody to PMAIP1

  • 货号:

    P42833
  • 别名:

    APR; NOXA
  • 产品上架时间:

    2024-01-01
  • 应用:

    IHC
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q13794
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥1980

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Rabbit Polyclonal Antibody to PMAIP1

Description

Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1?By similarity. Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1.

Specification

Aliases APR; NOXA
Entrez GeneID 5366;
Swissprot Q13794
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Full length fusion protein
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

IHC 1/50-1/200

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#P42833