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Western blot analysis of extracts from COLO205 cells, using RRM2B antibody P42742.

Rabbit Polyclonal Antibody to RRM2B

  • 货号:

    P42742
  • 别名:

    DKFZp686M05248; MGC102856; MGC42116; p53-inducible ribonucleotide reductase small subunit 2 homolog; p53-inducible ribonucleotide reductase small subunit 2-like protein
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB
  • 反应种属:

    Human,Mouse,Rat
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q7LG56
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥1980

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Rabbit Polyclonal Antibody to RRM2B

Description

Plays a pivotal role in cell survival by repairing damaged DNA in a p53/TP53-dependent manner. Supplies deoxyribonucleotides for DNA repair in cells arrested at G1 or G2. Contains an iron-tyrosyl free radical center required for catalysis. Forms an active ribonucleotide reductase (RNR) complex with RRM1 which is expressed both in resting and proliferating cells in response to DNA damage.Tanaka H., Nature 404:42-49(2000).Ugai H., Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases.

Specification

Aliases DKFZp686M05248; MGC102856; MGC42116; p53-inducible ribonucleotide reductase small subunit 2 homolog; p53-inducible ribonucleotide reductase small subunit 2-like protein
Entrez GeneID 50484;
Swissprot Q7LG56
WB Predicted band size 40kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen Synthesized peptide derived from Internal of human RRM2B.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/3000

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#P42742