Rabbit Polyclonal Antibody to ATP6V1H

Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates the ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system By similarity. Involved in the endocytosis mediated by clathrin-coated pits, required for the formation of endosomes.Liu B., Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases.Lu X., Immunity 8:647-656(1998).Hu R.-M., Proc. Natl. Acad. Sci. U.S.A. 97:9543-9548(2000).Lai C.-H., Genome Res. 10:703-713(2000).