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Western blot analysis of extracts from 3T3 cells, using TCF7L1 antibody P42640.

Rabbit Polyclonal Antibody to TCF7L1

  • 货号:

    P42640
  • 别名:

    Transcription factor 7-like 1; HMG box transcription factor 3; TCF-3; TCF7L1; TCF3
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB
  • 反应种属:

    Human,Mouse
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q9HCS4
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥1980

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Rabbit Polyclonal Antibody to TCF7L1

Description

Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. Necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis By similarity. Down-regulates NQO1, leading to increased mitomycin c resistance.Sagara N., Cancer Res. 60:5959-5962(2000).Hillier L.W., Nature 434:724-731(2005).Castrop J., Nucleic Acids Res. 20:611-611(1992).

Specification

Aliases Transcription factor 7-like 1; HMG box transcription factor 3; TCF-3; TCF7L1; TCF3
Entrez GeneID 83439;
Swissprot Q9HCS4
WB Predicted band size 63kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse
Immunogen Synthesized peptide derived from internal of human TCF7L1.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/3000

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#P42640