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Western blot analysis of extracts from HeLa cells, using DOCK1 antibody P42383.

Rabbit Polyclonal Antibody to DOCK1

  • 货号:

    P42383
  • 别名:

    180 kDa protein downstream of CRK; dedicator of cytokinesis protein 1; DOC1; DOCK180;
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q14185
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥1980

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Rabbit Polyclonal Antibody to DOCK1

Description

Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1.Hasegawa H., Mol. Cell. Biol. 16:1770-1776(1996).Deloukas P., Nature 429:375-381(2004).Matsuda M., J. Biol. Chem. 271:14468-14472(1996).

Specification

Aliases 180 kDa protein downstream of CRK; dedicator of cytokinesis protein 1; DOC1; DOCK180;
Entrez GeneID 1793;
Swissprot Q14185
WB Predicted band size 215kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Synthesized peptide derived from internal of human DOCK1.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/3000

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#P42383