Rabbit Polyclonal Antibody to CLN6

This gene is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function.Ota T., Nat. Genet. 36:40-45(2004).The MGC Project Team; Genome Res. 14:2121-2127(2004).Mole S.E., Exp. Cell Res. 298:399-406(2004).