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Western blot analysis using LAL mouse mAb against C6 (1), C2C12 (2), COS-7 (3), PC-12 (4), NIH/3T3 (5), Raw264.7 (6), F9 (7), mouse brain (8), mouse liver (9), mouse kidney (10), K562 (11), and HT1080 (12) cell lysate.

Immunofluorescence analysis of HeLa cells using Visfatin(PBEF) mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)

Flow cytometric analysis of K562 cells using Visfatin(PBEF) mouse mAb (green) and negative control (red).

Flow cytometric analysis of PC-12 cells using Visfatin(PBEF) mouse mAb (green) and negative control (red).

Immunohistochemical analysis of paraffin-embedded liver cancer tissues using Visfatin(PBEF) mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded colon cancer tissues using Visfatin(PBEF) mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using Visfatin(PBEF) mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using Visfatin(PBEF) mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded rat kidney tissues using Visfatin(PBEF) mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded rabbit liver tissues using Visfatin(PBEF) mouse mAb with DAB staining.

试 HOT

Mouse Monoclonal Antibody to PBEF1

货号：
20188
别名：
VF; PBEF; PBEF1; VISFATIN; NAMPT
产品上架时间：
2024-03-03
应用：
WB,IHC,IF,FCM
反应种属：
Human, Rat, Mouse, Monkey, Rabbit
抗体类型：
Primary antibody
Swissprot：
P43490
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Mouse Monoclonal Antibody to PBEF1

Description
PBEF1: nicotinamide phosphoribosyltransferase. This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It also activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.

Description

PBEF1: nicotinamide phosphoribosyltransferase. This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It also activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.

References
1. Mol Cell Biol. 1994 Feb;14(2):1431-7. 2. Eur J Immunol. 2002 Nov;32(11):3225-34.

Specification
Aliases	VF; PBEF; PBEF1; VISFATIN; NAMPT
Entrez GeneID	10135
Swissprot	P43490
clone	1D3A12
Host/Isotype	Mouse IgG1
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Rat, Mouse, Monkey, Rabbit
Immunogen	Purified recombinant fragment of PBEF1 (aa338-479) expressed in E. Coli.
Formulation	Ascitic fluid containing 0.03% sodium azide.