Rabbit Polyclonal Antibody to STRAD

Description
Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation

References
Scanlan M.J., Cancer Immun. 1:4-4(2001). Ota T., Nat. Genet. 36:40-45(2004). Baas A.F., EMBO J. 22:3062-3072(2003).

Specification
Aliases	STE20-related adapter protein; STRAD alpha; Serologically defined breast cancer antigen NY-BR-96; STRAD; LYK5
Entrez GeneID	92335;
Swissprot	Q7RTN6
WB Predicted band size	46kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	Synthesized peptide derived from internal of human STRAD.
Formulation	Purified antibody in PBS with 0.05% sodium azide.

Application
WB	1/500-1/3000
ELISA	1:20000-1:40000