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Western blot analysis of extracts from Jurkat cells, using MBD3 antibody P41897.
Rabbit Polyclonal Antibody to MBD3
-
货号：
P41897 -
别名：
Methyl-CpG-binding domain protein 3; Methyl-CpG-binding protein MBD3; MBD3; -
应用：
WB -
反应种属：
Human,Mouse -
抗体类型：
Primary antibody -
Swissprot：
O95983 -
规格：
-
数量：
-+ -
说明书：
目录价¥1980
Rabbit Polyclonal Antibody to MBD3
Description |
|---|
Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself (. Binds to DNA with a preference for sites containing methylated CpG dinucleotides (in vitro). Binds to a lesser degree DNA containing unmethylated CpG dinucleotides (). Recruits histone deacetylases and DNA methyltransferases.Hendrich B., Mol. Cell. Biol. 18:6538-6547(1998).Grimwood J., Nature 428:529-535(2004).Tatematsu K., Genes Cells 5:677-688(2000). |
Specification |
|
|---|---|
| Aliases | Methyl-CpG-binding domain protein 3; Methyl-CpG-binding protein MBD3; MBD3; |
| Entrez GeneID | 53615; |
| Swissprot | O95983 |
| WB Predicted band size | 33kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Synthesized peptide derived from C-terminal of human MBD3. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/3000 |
For Reseach Only
Application Key：WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
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